To Enable/Disable Autocomplete in Outlook, try the following:
1. Open Outlook, click Tools – Options
2. Click “Email Options” button then “Advanced Email Options”
3. Check/Uncheck “Suggest names while completing To, Cc,
Bcc fields” to enable/disable Autocomplete.
4. Click OK,OK, Apply & OK.

This should enable or disable AutoComplete in Outlooka s you need.
If you are an organisation and want to enable/disable Autocomplete on
all your network domain computers then you can use Group Policy to disable from Windows Registry
Look for the key “ShowAutoSug” key under
[HKEY_CURRENT_USER\Software\Microsoft\Office\11.0\Outlook\Preferences\]
and set its value as follows
“0? – Disable Autocomplete
“1? – Enable Autocomplete
NOTE: Depending on Office version the registry path may vary for
instance as "10" or "11"